Two sample MR report
GBP3_Endothelial Cell (Endo) against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 20 | 0.0119594 | 0.0472133 | 0.8029018 |
| Weighted median | 20 | 0.0189358 | 0.0072407 | 0.0089181 |
| Inverse variance weighted | 20 | 0.0114503 | 0.0054575 | 0.0358997 |
| Simple mode | 20 | 0.0253584 | 0.0118662 | 0.0458164 |
| Weighted mode | 20 | 0.0250924 | 0.0119708 | 0.0496927 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 19.72959 | 18 | 0.3482474 |
| Inverse variance weighted | 19.72972 | 19 | 0.4110038 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0004272 | 0.0393298 | 0.9914533 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0003634 | 0 | TRUE | 0.0702482 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
